We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
International Journal of Periodontics & Restorative Dentistry



Forgotten password?


Int J Periodontics Restorative Dent 13 (1993), No. 1     1. Jan. 1993
Int J Periodontics Restorative Dent 13 (1993), No. 1  (01.01.1993)

Page 85-92

Melanin Repigmentation After Gingivectomy: A 5-Year Clinical and Transmission Electron Microscopic Study in Humans
Bergamaschi / Kon / Doine / Ruben
The epithelium-melanin unit is formed by the melanocytes and keratinocytes. There is little information available about the behavior of melonocytes after surgical injury Five white patients with comparable gingival pigmentation underwent gingivectomy to remove bandlike melanin pigmentations for cosmetic reasons Biopsy specimens were taken from gingvectomy sites and healing areas 2, 3, 6, 7, 75, 50, and 780 days and 15, 3, and 5 years after the procedure. Transmission electron microscopic study revealed melanocytes in the process of migration and undergoing mitosis 6 and 7 days postoperatively. These cells exhibited, in the 15-day specimens, renewal of their dendritic processes and the four different stages of melanosome development. Kerotinocytes were devoid of pigmented material until 50 days postoperatively. Clinically, the intensity of the pigmentation varied among the patients. Two reached baseline coloration 1.5 years post-surgery, white three returned to baseline coloration by 3 years postsurgery. Thus, gingival resective procedures, if performed solely for cosmetic reasons, offer no permanent results.