We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
International Journal of Periodontics & Restorative Dentistry



Forgotten password?


Int J Periodontics Restorative Dent 33 (2013), No. 5     15. Aug. 2013
Int J Periodontics Restorative Dent 33 (2013), No. 5  (15.08.2013)

Page 641-649, doi:10.11607/prd.0989, PubMed:23998160

Effects of Enamel Matrix Derivative and Basic Fibroblast Growth Factor with β-Tricalcium Phosphate on Periodontal Regeneration in One-Wall Intrabony Defects: An Experimental Study in Dogs
Shirakata, Yoshinori / Takeuchi, Naoshi / Yoshimoto, Takehiko / Taniyama, Katsuyoshi / Noguchi, Kazuyuki
This study evaluated the effects of enamel matrix derivative (EMD) and basic fibroblast growth factor (bFGF) with β-tricalcium phosphate (β-TCP) on periodontal healing in intrabony defects in dogs. One-wall intrabony defects created in dogs were treated with β-TCP alone (β-TCP), EMD with β-TCP (EMD/β-TCP), bFGF with β-TCP (bFGF/β-TCP), and a combination of each (EMD/bFGF/β-TCP). The amount of new bone formation was not significant for any group. The EMD/bFGF/β-TCP group induced significantly greater new cementum formation than the β-TCP and bFGF/β-TCP groups and, although not significantly, formed more new cementum than the EMD/β-TCP group. These findings indicate that EMD/bFGF/β-TCP treatment is effective for cementum regeneration.