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International Journal of Periodontics & Restorative Dentistry



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Int J Periodontics Restorative Dent 34 (2014), No. 4     3. July 2014
Int J Periodontics Restorative Dent 34 (2014), No. 4  (03.07.2014)

Page 530-539, doi:10.11607/prd.1857, PubMed:25006770

Soft Tissue Healing in Alveolar Socket Preservation Technique: Histologic Evaluations
Pellegrini, Gaia / Rasperini, Giulio / Obot, Gregory / Farronato, Davide / Dellavia, Claudia
After tooth extraction, 14 alveolar sockets were grafted with porous bovine bone mineral particles and covered with non-cross-linked collagen membrane (test group), and 14 alveolar sockets were left uncovered. At 5 and 12 weeks, microvascular density (MVD), collagen content, and amount of lymphocytes (Lym) T and B were analyzed in soft tissue. At 5 weeks, MVD was significantly lower and Lym T was significantly higher in tests than in controls (P < .05). At 12 weeks no differences were found. Placement of resorbable membrane seems to induce an initial and transient modification of the normal wound healing process of the soft tissue.