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International Journal of Periodontics & Restorative Dentistry



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Int J Periodontics Restorative Dent 34 (2014), No. 4     3. July 2014
Int J Periodontics Restorative Dent 34 (2014), No. 4  (03.07.2014)

Page 550-557, doi:10.11607/prd.1737, PubMed:25006772

Maxillary Anterior Ridge Augmentation with Recombinant Human Bone Morphogenetic Protein 2
Edmunds, Ryan K. / Mealey, Brian L. / Mills, Michael P. / Thoma, Daniel S. / Schoolfield, John / Cochran, David L. / Mellonig, Jim
No human studies exist on the use of recombinant human bone morphogenetic protein 2 (rhBMP-2) on an absorbable collagen sponge (ACS) as a sole graft material for lateral ridge augmentation in large ridge defect sites. This series evaluates the treatment outcome of maxillary anterior lateral ridge augmentation with rhBMP-2/ACS. Twenty patients were treated with rhBMP-2/ACS and fixation screws for space maintenance. Cone beam volumetric tomography measurements were used to determine gain in ridge width, and a bone core biopsy was obtained. The mean horizontal ridge gain was 1.2 mm across sites, and every site gained width.