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International Journal of Periodontics & Restorative Dentistry
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Int J Periodontics Restorative Dent 35 (2015), No. 1     5. Jan. 2015
Int J Periodontics Restorative Dent 35 (2015), No. 1  (05.01.2015)

Page 84-91, doi:10.11607/prd.1849, PubMed:25734710


Clinical and Histologic Comparative Study of Subepithelial Connective Tissue Graft and Extracellular Matrix Membrane. A Preliminary Split-Mouth Study in Humans
Santagata, Mario / Tartaro, Gianpaolo / D'Amato, Salvatore
The purpose of this randomized, controlled, split-mouth study was to compare the behavior of the extracellular matrix membrane (EMM) with autogenous subepithelial connective tissue graft (SCTG) when used as a biologic barrier in the covering of immediate implant placement after modified edentulous ridge expansion. A total of five patients between 40 and 59 years of age (three men, two women) were selected for this study and randomly assigned to one of two groups: EMM (test) or SCTG (control). Treatments were randomly assigned at the same surgical appointment. A total of 29 screw-shaped titanium implants were inserted. Clinical examinations and prophylaxis were performed in recall sessions at 2, 4, and 16 weeks postsurgery. A soft tissue biopsy was performed at both sides 4 months postsurgery. This study indicates that both procedures were effective and predictable in barrier membrane coverage after bone expansion and immediate implant placement. The use of EMM may be a valid alternative to SCTG as a biologic barrier in bone expansion procedures. The use of EMM eliminates the need for the palatal donor site and, as such, provides a less invasive solution.