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International Journal of Periodontics & Restorative Dentistry
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Int J Periodontics Restorative Dent 35 (2015), No. 6     30. Oct. 2015
Int J Periodontics Restorative Dent 35 (2015), No. 6  (30.10.2015)

Page 824-833, doi:10.11607/prd.2330, PubMed:26509986


Platelet-Derived Growth Factor-Mediated Guided Bone Regeneration in Immediate Implant Placement in Molar Sites with Buccal Bone Defects
Santana, Ronaldo B. / Santana, Carolina M.M. / Dibart, Serge
This study compared the clinical outcomes of recombinant human plateletderived growth factor BB and beta-tricalcium phosphate (rhPDGF-BB/βTCP) with guided bone regeneration (GBR) in immediate implant placement in molar extraction sockets with buccal bone defects versus conventional implant placement. Twenty-eight implants were placed in fourteen patients. Clinical and radiographic evaluations assessed peri-implant soft and hard tissue parameters after 12 months. No implants were lost during the 1-year observation period, yielding a survival rate of 100%. Similar clinical and radiographic parameters were observed for both treatment groups. Use of rhPDGF-BB/βTCP and GBR in immediate implants in molars was as successful as conventional implant placement in fully healed extraction sites.