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International Journal of Periodontics & Restorative Dentistry
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Int J Periodontics Restorative Dent 36 (2016), No. 6     14. Oct. 2016
Int J Periodontics Restorative Dent 36 (2016), No. 6  (14.10.2016)

Page 796-805, doi:10.11607/prd.2842, PubMed:27740640


Enamel Matrix Derivative Proteins in Combination with a Flapless Approach for Periodontal Regeneration of Intrabony Defects: A 2-Year Prospective Case Series
Aimetti, Mario / Ferrarotti, Francesco / Mariani, Giulia Maria / Fratini, Aiano / Giraudi, Marta / Romano, Federica
The present case series evaluated the potential benefits of a flapless approach in the regenerative treatment of residual deep intrabony defects. In each of 11 patients, one periodontal defect with an intrabony component of ≥ 3 mm was treated regeneratively using enamel matrix derivative combined with a closed surgical technique. Clinical and radiographic parameters were recorded at baseline and at 12 and 24 months postoperatively. All defects experienced favorable clinical and radiographic outcomes at the 24-month follow-up. When considering only sites located in the anterior region, all experienced complete pocket closure.