Int J Periodontics Restorative Dent 36 (2016), No. 6 14. Oct. 2016
Int J Periodontics Restorative Dent 36 (2016), No. 6 (14.10.2016)
Page 806-815, doi:10.11607/prd.3066, PubMed:27740641
Tissue Integration of a Volume-Stable Collagen Matrix in an Experimental Soft Tissue Augmentation Model
Ferrantino, Luca / Bosshardt, Dieter / Nevins, Myron / Santoro, Giacomo / Simion, Massimo / Kim, David
Reducing the need for a connective tissue graft by using an efficacious biomaterial is an important task for dental professionals and patients. This experimental study aimed to test the soft tissue response to a volume-stable new collagen matrix. The device demonstrated good stability during six different time points ranging from 0 to 90 days of healing with no alteration of the wound-healing processes. The 90-day histologic specimen demonstrates eventual replacement of most of the matrix with new connective tissue fibers.