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International Journal of Periodontics & Restorative Dentistry



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Int J Periodontics Restorative Dent 37 (2017), No. 2     17. Feb. 2017
Int J Periodontics Restorative Dent 37 (2017), No. 2  (17.02.2017)

Page 218-225, doi:10.11607/prd.2776, PubMed:28196162

The Use of Recombinant Human Platelet-Derived Growth Factor for Maxillary Sinus Augmentation
Kubota, Atsushi / Sarmiento, Hector / Alqahtani, Mohammed Saad / Llobell, Arturo / Fiorellini, Joseph P.
The maxillary sinus augmentation procedure has become a predictable treatment to regenerate bone for implant placement. The purpose of this study was to evaluate the effect of recombinant human platelet-derived growth factor BB (rhPDGF-BB) combined with a deproteinized cancellous bovine bone graft for sinus augmentation. The lateral window approach was used for maxillary sinuses with minimal residual bone. After a healing period of 4 months, dental implants were placed and then restored following a 2-month osseointegration period. The result demonstrated increased bone height and ISQ values and a 100% survival rate. This study indicates that the addition of rhPDGF-BB to deproteinized cancellous bovine bone accelerated the healing period in maxillary sinuses with minimal native bone.